Response to DSBs
| PAG Title | Response to DSBs |
| PAG ID | WIG001819 |
| Type | P |
| Source Link |  Spike |
| Publication Reference | NA |
| PAG Description | DNA double-strand breaks (DSBs) arise in cells from and exogenous and endogenous attacks on the DNA backbone. Ionizing radiation (IR)] is the main exogenous cause of DSB. Proper repair of DSBs is critical and essential for maintaining genomic integrity and stability. Eukaryotic organisms have evolved multi-potent and efficient mechanisms to repair DSBs that are primarily divided into two types of pathways: nonhomologous end joining (NHEJ) and homologous recombination (HR). |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 2,708 |
| Information Content | Rich |
| Other IDs | SPIKE00004 |
| Base PAG ID | WIG001819 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
">
Something else? Please send us an email!